Mario Gotze scored the only goal of the game as Riyad Mahrez made his Manchester City debut in a 1-0 loss to Borussia Dortmund at the International Champions Cup.
Mahrez debuted in Chicago on Friday after completing a club-record £60million transfer from Leicester City earlier this month.
The Algeria star showed glimpses of his quality for the Premier League champions and he almost scored before half-time via a set-piece but undermanned City fell to Dortmund at Soldier Field.
Gotze – wearing the captain's armband – scored from the penalty spot in the 28th minute after Dortmund team-mate and United States star Christian Pulisic was fouled by Oleksandr Zinchenko.
The World Cup deprived the Chicago crowd of a host of stars, with Gabriel Jesus, Sergio Aguero, Kyle Walker, Danilo, Vincent Kompany, John Stones, Raheem Sterling, Ilkay Gundogan, Kevin De Bruyne, Fabian Delph, Bernardo Silva, David Silva, Benjamin Mendy, Fernandinho, Nicolas Otamendi and Ederson absent for the Premier League champions.
Pep Guardiola's City, however, still fielded Mahrez and Claudio Bravo, with Leroy Sane and Aymeric Laporte on the bench.
Bundesliga outfit Dortmund – who downed Austria Vienna 1-0 in Lucien Favre's bow last week – were also without the likes of Raphael Guerreiro, Shinji Kagawa, Roman Burki and new signings Thomas Delaney and Manuel Akanji, though Gotze and Pulisic took part.
City made a lively start as the English side – led by Mahrez – enjoyed some success down the left-hand side without really troubling Marwin Hitz.
Dortmund grew into the game as the half wore on and they hit the front approaching the half-hour mark.
Zinchenko was exposed by Pulisic, who received the ball and drew a foul from the Ukrainian utility inside the penalty area after Dortmund dispossessed City before Gotze converted the spot-kick.
City were caught out at the back again when Alexander Isak rounded Bravo but the Swede found the side netting from an acute angle moments later.
Debutant Mahrez almost equalised on the stroke of half-time but his free-kick was kept out by Hitz.
Joe Hart – who is seeking a permanent move away from the Etihad Stadium – replaced Bravo at the interval, while Dortmund changed all 10 outfield players for the second half.
Dortmund found the back of the net again in the second half but Max Philipp's effort was ruled out for offside, much to the relief of City.
Hart was called into action with 19 minutes remaining, the out-of-favour former England number one – who spent last season on loan at West Ham – denying Jadon Sancho.
|Injured Halep withdraws from Connecticut Open|
|Cipriani fined £2,000 by Gloucester|
|Mourinho will be sacked before Christmas, says Sharpe|
|England face record chase after Kohli smashes India to huge lead|
|Ozil captaining Arsenal a miracle - Hoeness|
|Japan players apologise for ´thoughtless, careless´ actions at Asian Games|
|Henry wants Bordeaux job, Wenger confirms|
|Pogba too inconsistent and not a leader, claims Scholes|
|PCB chairman Sethi resigns in letter to Pakistan prime minister Imran Khan|
|US Open comes too soon for Tsonga|
|Unpredictable results making 2018 F1 season a classic - Wolff|
|Mendy restricts phone use on Guardiola advice|
|Modric brands Inter approach claim ´the greatest nonsense in history´|
|Runners and Ryders: Olesen leapfrogs Poulter into last Team Europe berth|
|Kenedy escapes further action over Camarasa kick|
|England´s Bairstow suffers ´small fracture´ to finger|
|Gonalons joins Sevilla on loan from Roma|
|Modric, Ronaldo and Salah final UEFA Player of the Year nominees|
|Tottenham to play opening Champions League home match at Wembley|
|Karius´ Champions League blunders did not lead to Alisson signing - Klopp|
|Leeds considered €20m Conte offer before turning to Bielsa|
|Modric, Rakitic lead new era for World Cup finalists Croatia|
|Storm´s Chambers banned for three weeks, Smith injury not serious|
|Porte to race Vuelta after recovering from Tour crash|
|The Career Golden Masters: A run-down of Djokovic´s magnificent record|
|Japan send home four basketball players from Asian Games amid prostitution scandal|
|Rugby tackle bags helping Liverpool´s Alisson with Premier League life|
|Federer raring to go at US Open after Djokovic defeat|
|Chelsea boss Sarri plans to give up smoking|
|Alonso´s Toyota team stripped of Silverstone victory|
|Ceballos: No issue with former Real Madrid boss Zidane|
|MLS Review: Martinez equals single-season goalscoring record|
|Astros avoid sweep with win over Athletics|
|Seppi advances, Paire exits Winston-Salem|
|Bale feeling good as Madrid eye sweep of trophies|
|You can´t leave a house three-quarters built – Neville urges United to back Mourinho|
|Dodgers slugger Machado leaves game after being struck by pitch|
|Harden says Carmelo will ´be a good fit´ for Rockets|
|Morata: I never considered Chelsea exit|
|Gavrilova kicks off title defence in New Haven|
|Lopetegui pleased with Bale and Real Madrid after LaLiga opener|
|It´s a very special moment – Djokovic revels in Golden Masters achievement|
|Sorrentino thanks Ronaldo for support after injury|
|Twins place Santana on DL with finger injury|
|Yankees´ Gregorius suffers ´pretty significant´ heel bruise|
|Snedeker ends PGA Tour drought with Wyndham Championship win|
|Spalletti unconcerned despite Inter´s underwhelming start|
|Djokovic makes history with Masters clean sweep in Cincinnati|
|Real Madrid 2 Getafe 0: Bale gives Lopetegui first LaLiga win|
|IndyCar driver Wickens taken to hospital after crash|
|Sherman calls for NFL to scrap ´idiotic´ helmet rule|
|Sassuolo 1 Inter 0: New-look Nerazzurri given early reality check|
|Hughton: Shock United win does not alter scale of Brighton´s task|
|Navas keeps place as Courtois waits on Madrid debut|
|Ndidi signs long-term Leicester City contract|
|Pandya tears through feeble England to put India in command|
|Alonso creates motorsport history with victory at Silverstone|
|Kovacic: Chelsea and Sarri believe in me|
|Brighton loss a big lesson for United – Pogba|
|Mistakes hit United´s confidence - Mourinho|
|Brighton and Hove Albion 3 Manchester United 2: Murray lifts Seagulls to another win over Mourinho|
|Quickfire Moon treble sets up Rhinos win|
|Manchester City celebrate win with Silva´s son|
|Brentford 2 Sheffield Wednesday 0: Maupay stars as Bees buzz by Owls|
|Guardiola delighted with fit and firing Aguero|
|Waring marks 200th event with maiden title in Gothenburg|
|Guardiola dismisses Mourinho´s ´disrespectful´ accusation|
|Hulkenberg proud to survive in F1´s pay driver era|
|It´s here, it´s real, get on with it - Dyche dismisses Europa League excuse|
|Grujic agrees Liverpool extension, joins Hertha on loan|