For the third time in four years, reigning NFL Super Bowl champions the New England Patriots are the top seed in the AFC and have homefield throughout the playoffs.
The Patriots have played in six successive AFC championship games, and it will be a tough task for the Tennessee Titans to prevent New England from reaching a seventh.
The Titans (10-7) rallied from a 21-3 deficit to pull off a 22-21 wildcard win over the Kansas City Chiefs at Arrowhead Stadium.
Titans quarterback Marcus Mariota will have to be at his best on Saturday to beat the Patriots (13-3) at Gillette Stadium.
WILL THE PATRIOTS REMAIN FOCUSED?
Quarterback Tom Brady and head coach Bill Belichick, as well as others, were forced to answer questions all week after ESPN reported that there was turmoil atop the organisation.
Reports of discontent were quickly denied, but it would be only human nature for such a distraction to affect preparation. Still, if there is one thing the Patriots have done better than most under Belichick, it is quieting the noise.
CAN HENRY STAY HOT?
The Patriots had the NFL's 20th-ranked rush defense during the regular season, allowing a 100-yard rusher four times. The last two came in December when Miami's Kenyan Drake and Pittsburgh's Le'Veon Bell joined Kansas City's Kareem Hunt and Los Angeles Chargers running back Melvin Gordon as players to eclipse the century mark against the Patriots.
Derrick Henry is coming off a 156-yard effort against the Chiefs as Tennessee's offensive line wore down Kansas City. It was Henry's third 100-yard game this season as he led the Titans during the regular season with 744 yards while splitting carries with DeMarco Murray. With Murray injured, Henry was the workhorse against the Chiefs and will have to carry the load again in Foxborough since Murray has been ruled out.
CAN THE TITANS CONTAIN GRONKOWSKI?
The Titans did not allow a tight end to have 100 receiving yards in a game this season. They were getting burned by Chiefs tight end Travis Kelce in the first half of last week's game, which changed dramatically when Kelce was injured just before half-time. Kelce had four catches for 66 yards and a touchdown in the first half.
The Titans now have to contend with Patriots tight end Rob Gronkowski, who led New England with 69 catches for 1,084 yards and eight touchdowns in only 14 games.
Gronkowski has gone for more than 140 yards in two of his last three games, but the Titans have excellent safeties in Johnathan Cyprien and Kevin Byard, who led the NFL with eight interceptions this season.
|Everybody wants to play under him – Ozil pays tribute to Wenger|
|Conte defends Chelsea record compared to Mourinho|
|LaLiga strugglers Espanyol show Flores the door|
|Messi is an alien but Sevilla can bring Barcelona back down to Earth, insists Montella|
|Four in a row for Wigan as Saints thrash Huddersfield|
|Reims´ latest vintage secure promotion to Ligue 1|
|Gloucester cruise into Challenge Cup final|
|Quiros claims one-shot lead despite rollercoaster round two|
|Millwall 0 Fulham 3: Sessegnon on target as Jokanovic´s side go second|
|Curry to begin modified practices on Saturday|
|Ancelotti welcomes Arsenal links, praises Wenger decision|
|Nadal produces ´best match of tournament´ as Dimitrov beats doubles partner|
|I think Arsenal would be good for a German coach - Podolski|
|Wilshere, Ramsey, Mertesacker and the best social media reaction to Wenger´s Arsenal departure|
|Watson haunts Royals with Super Kings hundred|
|Selby bracing himself for tough title defence|
|Exeter left ´disappointed´ by Ampadu transfer verdict|
|Froome thrilled with ´perfect´ build-up to Giro|
|Copa del Rey glory a good way to put European exit behind us, says Valverde|
|LMA hails Wenger´s impact at Arsenal|
|Wenger passes the torch as Arsenal face up to his formidable legacy|
|Gazidis: Arsenal cannot replace Wenger – we need a new path|
|Ronnie rivals never doubted Crucible attendance of ´snooker´s Tiger Woods´|
|Van Bronckhorst using Wenger´s methods at Feyenoord|
|Former NFL lineman Evan Mathis´ 1952 Mickey Mantle card sells for $2.88M|
|Wasps forward Johnson suspended for failed drugs test|
|I´d break another finger to win the Copa del Rey - Rakitic|
|Arsene Wenger: The Arsenal manager´s worst moments|
|Wright: More Arsenal changes needed after Wenger exit|
|Guardiola wishes Iniesta the best ahead of potential Barcelona exit|
|Real football people appreciate Wenger - Moyes, Warnock and more pay tribute|
|Guardiola set for contract talks with Manchester City|
|Controversial Slater score helps Storm to victory|
|Liverpool top, DVDs just invented and no Harry Potter – The world when Wenger joined Arsenal|
|Heynckes cannot compare Lewandowski and Ronaldo|
|Ronaldinho, Ronaldo, Messi, Mbappe and more – the stars Wenger claims he could have signed|
|Ferguson: Rival, colleague and friend Wenger is one of the greatest|
|Gattuso wary of challenge for Milan´s European place|
|Neuer returns to Bayern training after seventh-month absence|
|Wembley no advantage for Spurs in semi-final, warns Mourinho|
|WATCH: Dez Bryant works out with Odell Beckham Jr. as rumors swirl|
|PSG, Monaco, the CSL, France? - Wenger´s possible next moves|
|Rematches, rivalries and a mouth-watering Wembley clash – The pick of the 2018 NFL schedule|
|Wenger ´an example´ to foreign Premier League managers like Benitez|
|Wilshere: Wenger is like a father|
|Guardiola wants Wenger to find new role in football|
|Henry: Wenger´s Arsenal legacy is untouchable|
|Mourinho: Wenger feud shows how much I respect him|
|Conte: Top four still possible for Chelsea|
|Frizell inspires Highlanders win over Blues, Lions beat Waratahs|
|Majestic Nadal hammers Thiem in Monte Carlo|
|Aguero out for the season - Guardiola|
|Wenger´s 22-year Arsenal tenure will not be matched, says Conte|
|Celtic would let Rodgers move to Arsenal|
|Squillaci, Cech & Wenger´s worst signings at Arsenal|
|Heynckes: I cannot imagine Wenger at another club|
|Thank you Arsene - Emery pays tribute to Wenger|
|Fabregas and Van Persie join tributes to Arsenal boss Wenger|
|Smith confirmed as England national selector|
|1,228 matches and seven FA Cups - Wenger at Arsenal in Opta numbers|
|Mertesacker ´emotional´ as Wenger announces Arsenal departure|
|Ancelotti, Tuchel, Henry – Where do Arsenal turn after Wenger?|
|Klopp doesn´t want Liverpool to chase Golden Boot for Salah|
|´The Arsene Wenger Stadium´ - Former Arsenal players call for tribute|
|Wenger was so good ´it was scary´, says Merson|
|Shields requests to be released for England duty|
|Khan: ´Cheat´ Alvarez got off lightly|
|I fell in love with playing for Wenger - Winterburn|
|Van der Sar urges Kluivert to continue Ajax development|
|Cockerill signs Edinburgh contract extension|